Murray Hill is a neighborhood in midtown Manhattan in New York City. In 1999, Manhattan Community Board 6 – of which Murray Hill is part – defined the boundaries as East 34th Street to the south, East 40th Street to the north, Madison Avenue to the west, and Third Avenue to the east.

The community is home to the CUNY Graduate Center which share the landmark former B. Altman Building with the New York Public Library's Science, Industry and Business Library (SIBL) and with Oxford University Press. The neighborhood is also home to Stern College for Women of Yeshiva University, The Morgan Library & Museum, Scandinavia House–The Nordic Center in America, The Mexican Cultural Institute of New York, and a historically notable private institution, the Union League Club of New York. The area also includes 10 East 40th Street, an example of art deco architecture.

On January 29, 2008, the Whitney Museum of American Art branch gallery at what had been the Philip Morris headquarters opposite Grand Central Terminal closed after a 25-year run. For around fifty years the neighborhood has been home to the National Review, the conservative journal of opinion founded by William F. Buckley, Jr., most of that time at 150 East 35th Street, currently at 215 Lexington Avenue at 33rd Street. 150 East 35th Street was purchased by Yeshiva University.